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An MDR1 promoter allele with higher promoter activity is common in clinically isolated strains of Candida albicans

In the opportunistic fungal pathogen Candida albicans, up-regulation of MDR1, encoding an efflux transporter, leads to increased resistance to the antifungal drug fluconazole. Antifungal resistance has been linked to several types of genetic change in C. albicans, including changes in genome structu...

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Hlavní autoři: Bruzual, Igor, Kumamoto, Carol A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874411/
https://ncbi.nlm.nih.gov/pubmed/21972105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00438-011-0650-z
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