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The pioneer translation initiation complex is functionally distinct from but structurally overlaps with the steady-state translation initiation complex

The bulk of cellular proteins derive from the translation of eukaryotic translation initiation factor (eIF)4E-bound mRNA. However, recent studies of nonsense-mediated mRNA decay (NMD) indicate that cap-binding protein (CBP)80-bound mRNA, which is a precursor to eIF4E-bound mRNA, can also be translat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chiu, Shang-Yi, Lejeune, Fabrice, Ranganathan, Aparna C., Maquat, Lynne E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC387415/
https://ncbi.nlm.nih.gov/pubmed/15059963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1170204
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