Mechanism and preclinical prevention of increased breast cancer risk caused by pregnancy

While a first pregnancy before age 22 lowers breast cancer risk, a pregnancy after age 35 significantly increases life-long breast cancer risk. Pregnancy causes several changes to the normal breast that raise barriers to transformation, but how pregnancy can also increase cancer risk remains unclear...

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Main Authors: Haricharan, Svasti, Dong, Jie, Hein, Sarah, Reddy, Jay P, Du, Zhijun, Toneff, Michael, Holloway, Kimberly, Hilsenbeck, Susan G, Huang, Shixia, Atkinson, Rachel, Woodward, Wendy, Jindal, Sonali, Borges, Virginia F, Gutierrez, Carolina, Zhang, Hong, Schedin, Pepper J, Osborne, C Kent, Tweardy, David J, Li, Yi
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2013
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874103/
https://ncbi.nlm.nih.gov/pubmed/24381245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00996
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