Synthesis and Evaluation of Anti-acetylcholinesterase Activity of 2-(2-(4-(2-Oxo-2-phenylethyl)piperazin-1-yl) ethyl)Isoindoline-1,3-dione Derivatives with Potential Anti-Alzheimer Effects

Objective(s): Alzheimer's disease (AD) is a neurodegenerative disorder in elderly patients. Decrease in cholinergic neurotransmission is the main known cause in the pathophysiology of the disease. Improvement and potentiation of the cholinergic system could be beneficial for treatment of the AD...

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Autores principales: Aliabadi, Alireza, Foroumadi, Alireza, Mohammadi-Farani, Ahmad, Garmsiri Mahvar, Mahdi
Formato: Artigo
Lenguaje:Inglês
Publicado: Mashhad University of Medical Sciences 2013
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874090/
https://ncbi.nlm.nih.gov/pubmed/24379961
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