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Synthesis and Evaluation of Anti-acetylcholinesterase Activity of 2-(2-(4-(2-Oxo-2-phenylethyl)piperazin-1-yl) ethyl)Isoindoline-1,3-dione Derivatives with Potential Anti-Alzheimer Effects

Objective(s): Alzheimer's disease (AD) is a neurodegenerative disorder in elderly patients. Decrease in cholinergic neurotransmission is the main known cause in the pathophysiology of the disease. Improvement and potentiation of the cholinergic system could be beneficial for treatment of the AD...

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Autors principals: Aliabadi, Alireza, Foroumadi, Alireza, Mohammadi-Farani, Ahmad, Garmsiri Mahvar, Mahdi
Format: Artigo
Idioma:Inglês
Publicat: Mashhad University of Medical Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874090/
https://ncbi.nlm.nih.gov/pubmed/24379961
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