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Investigating the Association of ApoE Genotypes with Blood-Brain Barrier Dysfunction Measured by Cerebrospinal Fluid-Serum Albumin Ratio in a Cohort of Patients with Different Types of Dementia

BACKGROUND: Since more than a decade ApoE is known to be a strong risk factor for Alzheimer's disease (AD); however, molecular pathways mediating this risk are still unclear. In recent years it has been hypothesized that ApoE might play a role in the disintegration of blood-brain barrier (BBB)....

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Detalhes bibliográficos
Main Authors: Karch, André, Manthey, Henrike, Ponto, Claudia, Hermann, Peter, Heinemann, Uta, Schmidt, Christian, Zerr, Inga
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874026/
https://ncbi.nlm.nih.gov/pubmed/24386372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084405
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