Dynamic Oscillation of Translation and Stress Granule Formation Mark the Cellular Response to Virus Infection

Virus infection-induced global protein synthesis suppression is linked to assembly of stress granules (SGs), cytosolic aggregates of stalled translation preinitiation complexes. To study long-term stress responses, we developed an imaging approach for extended observation and analysis of SG dynamics...

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Détails bibliographiques
Auteurs principaux: Ruggieri, Alessia, Dazert, Eva, Metz, Philippe, Hofmann, Sarah, Bergeest, Jan-Philip, Mazur, Johanna, Bankhead, Peter, Hiet, Marie-Sophie, Kallis, Stephanie, Alvisi, Gualtiero, Samuel, Charles E., Lohmann, Volker, Kaderali, Lars, Rohr, Karl, Frese, Michael, Stoecklin, Georg, Bartenschlager, Ralf
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873964/
https://ncbi.nlm.nih.gov/pubmed/22817989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.05.013
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