Concurrent erythropoietin and hypothermia treatment improve outcomes in a term nonhuman primate model of perinatal asphyxia

BACKGROUND: Up to 65% of untreated infants suffering from moderate to severe hypoxic-ischemic encephalopathy (HIE) are at risk of death or major disability. Therapeutic hypothermia (HT) reduces this risk to approximately 50% (number needed to treat 7-9). Erythropoietin (Epo) is a neuroprotective tre...

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Hauptverfasser: Traudt, Christopher M., McPherson, Ronald J., Bauer, Larry A., Richards, Todd L., Burbacher, Thomas M., McAdams, Ryan M., Juul, Sandra E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873854/
https://ncbi.nlm.nih.gov/pubmed/24192275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000355460
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