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13-cis-retinoic acid suppresses hippocampal cell division and hippocampal-dependent learning in mice

The active component of the acne drug Accutane is 13-cis-retinoic acid (RA), and it is highly teratogenic for the developing central nervous system. Very little is known, however, regarding the effect of this drug on the adult brain. Regions of the brain that may be susceptible to RA are those that...

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Detalhes bibliográficos
Main Authors: Crandall, James, Sakai, Yasuo, Zhang, Jinghua, Koul, Omanand, Mineur, Yann, Crusio, Wim E., McCaffery, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387382/
https://ncbi.nlm.nih.gov/pubmed/15051884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306336101
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