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Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade

Dopamine (DA) is a neurotransmitter involved in the control of locomotion, emotion, cognition, and reward. Administration of lithium salts is known to inhibit DA-associated behaviors in experimental animal models through unknown mechanisms. Here, we used a pharmacogenetic approach to show that DA ca...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Beaulieu, Jean-Martin, Sotnikova, Tatyana D., Yao, Wei-Dong, Kockeritz, Lisa, Woodgett, James R., Gainetdinov, Raul R., Caron, Marc G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387380/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15044694/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307921101
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