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Elucidating functional context within microarray data by integrated transcription factor focused gene-interaction and regulatory network analysis

Microarrays do not yield direct evidence for functional connections between genes. However, transcription factors (TFs) and their binding sites (TFBSs) in promoters are important for inducing and coordinating changes in RNA levels and thus represent the first layer of functional interaction. Similar...

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Detalhes bibliográficos
Main Authors: Werner, Thomas, Dombrowski, Susan, Zgheib, Carlos, Zouein, Fouad A., Keen, Henry L., Kurdi, Mazen, Booz, George W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873763/
https://ncbi.nlm.nih.gov/pubmed/23822978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1684/ecn.2013.0336
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