Arrestin-3 Binds c-Jun N-terminal Kinase 1 (JNK1) and JNK2 and Facilitates the Activation of These Ubiquitous JNK Isoforms in Cells via Scaffolding

Non-visual arrestins scaffold mitogen-activated protein kinase (MAPK) cascades. The c-Jun N-terminal kinases (JNKs) are members of MAPK family. Arrestin-3 has been shown to enhance the activation of JNK3, which is expressed mainly in neurons, heart, and testes, in contrast to ubiquitous JNK1 and JNK...

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Main Authors: Kook, Seunghyi, Zhan, Xuanzhi, Kaoud, Tamer S., Dalby, Kevin N., Gurevich, Vsevolod V., Gurevich, Eugenia V.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873585/
https://ncbi.nlm.nih.gov/pubmed/24257757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.510412
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