Distinct MicroRNA Expression Profile and Targeted Biological Pathways in Functional Myeloid-derived Suppressor Cells Induced by Δ(9)-Tetrahydrocannabinol in Vivo: REGULATION OF CCAAT/ENHANCER-BINDING PROTEIN α BY MicroRNA-690

Δ(9)-Tetrahydrocannabinol (THC), the major bioactive component of marijuana, has been shown to induce functional myeloid-derived suppressor cells (MDSCs) in vivo. Here, we studied the involvement of microRNA (miRNA) in this process. CD11b(+)Gr-1(+) MDSCs were purified from peritoneal exudates of mic...

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Detalhes bibliográficos
Main Authors: Hegde, Venkatesh L., Tomar, Sunil, Jackson, Austin, Rao, Roshni, Yang, Xiaoming, Singh, Udai P., Singh, Narendra P., Nagarkatti, Prakash S., Nagarkatti, Mitzi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873541/
https://ncbi.nlm.nih.gov/pubmed/24202177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.503037
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