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Expression of the Homeobox Gene HOXA9 in Ovarian Cancer Induces Peritoneal Macrophages to Acquire an M2 Tumor-Promoting Phenotype

Tumor-associated macrophages (TAMs) exhibit an M2 macrophage phenotype that suppresses anti-tumor immune responses and often correlates with poor outcomes in patients with cancer. Patients with ovarian cancer frequently present with peritoneal carcinomatosis, but the mechanisms that induce naïve per...

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Bibliografiske detaljer
Main Authors: Ko, Song Yi, Ladanyi, Andras, Lengyel, Ernst, Naora, Honami
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873497/
https://ncbi.nlm.nih.gov/pubmed/24332016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.09.017
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