Mucosal Pre-Exposure to Th17-Inducing Adjuvants Exacerbates Pathology after Influenza Infection

Mucosal vaccines are thought to confer superior protection against mucosal infectious diseases. In addition, mucosal routes of vaccine delivery preferentially induce the generation of T helper 17 (Th17) cells, which produce the cytokine IL-17. Th17 cells are critical in mediating vaccine-induced imm...

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Detalhes bibliográficos
Main Authors: Gopal, Radha, Rangel-Moreno, Javier, Fallert Junecko, Beth A., Mallon, Daniel J., Chen, Kong, Pociask, Derek A., Connell, Terry D., Reinhart, Todd A., Alcorn, John F., Ross, Ted M., Kolls, Jay K., Khader, Shabaana A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873493/
https://ncbi.nlm.nih.gov/pubmed/24183780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.09.012
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