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Protection against zinc toxicity by metallothionein and zinc transporter 1

Cells protect themselves from zinc toxicity by inducing proteins such as metallothionein (MT) that bind it tightly, by sequestering it in organelles, or by exporting it. In this study, the interplay between zinc binding by MT and its efflux by zinc transporter 1 (ZnT1) was examined genetically. Inac...

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Bibliographic Details
Main Author: Palmiter, Richard D.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC387349/
https://ncbi.nlm.nih.gov/pubmed/15041749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401022101
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