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Myeloid Cell Sirtuin-1 Expression Does Not Alter Host Immune Responses to Gram-Negative Endotoxemia or Gram-Positive Bacterial Infection

The role of sirtuin-1 (SIRT1) in innate immunity, and in particular the influence of SIRT1 on antimicrobial defense against infection, has yet to be reported but is important to define since SIRT1 inhibitors are being investigated as therapeutic agents in the treatment of cancer, Huntington’s diseas...

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Detalhes bibliográficos
Main Authors: Crotty Alexander, Laura E., Marsh, Brenda J., Timmer, Anjuli M., Lin, Ann E., Zainabadi, Kayvan, Czopik, Agnieszka, Guarente, Leonard, Nizet, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873454/
https://ncbi.nlm.nih.gov/pubmed/24386389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084481
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