Behavioral and Neurotransmitter Abnormalities in Mice Deficient for Parkin, DJ-1 and Superoxide Dismutase

Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by loss of neurons in the substantia nigra that project to the striatum and release dopamine. The cause of PD remains uncertain, however, evidence implicates mitochondrial dysfunction and oxidative stress. Although mos...

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Bibliographic Details
Main Authors: Hennis, Meghan R., Seamans, Katherine W., Marvin, Marian A., Casey, Bradford H., Goldberg, Matthew S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873453/
https://ncbi.nlm.nih.gov/pubmed/24386432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084894
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