Association of genetic variants in CDK6 and XRCC1 with the risk of dysplastic nevi in melanoma-prone families

Dysplastic nevi (DN) is a strong risk factor for cutaneous malignant melanoma (CMM), and it frequently occurs in melanoma-prone families. To identify genetic variants for DN, we genotyped 677 tagSNPs in 38 melanoma candidate genes that are involved in pigmentation, DNA repair, cell cycle control, an...

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Autores principales: Liang, Xueying, Pfeiffer, Ruth M., Li, Wen-Qing, Brossard, Myriam, Burke, Laura S., Wheeler, William, Calista, Donato, Fargnoli, Maria Concetta, Ghiorzo, Paola, Peris, Ketty, Bianchi-Scarra’, Giovanna, Chaudru, Valerie, Zelenika, Diana, Maeder, Dennis, Burdette, Laurie, Yeager, Meredith, Chanock, Stephen, Landi, Maria Teresa, Demenais, Florence, Tucker, Margaret A., Goldstein, Alisa M., Yang, Xiaohong R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873368/
https://ncbi.nlm.nih.gov/pubmed/23892592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.316
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