Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor

We have recently engineered an in vivo endothelial cell-specific retroviral gene transfer system and found that a single Kaposi's sarcoma (KS)-associated herpesvirus/human herpesvirus 8 gene encoding a G protein-coupled receptor (vGPCR), is sufficient to induce KS-like tumors in mice. By using...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Sodhi, Akrit, Montaner, Silvia, Patel, Vyomesh, Gómez-Román, José Javier, Li, Yi, Sausville, Edward A., Sawai, Earl T., Gutkind, J. Silvio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2004
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387332/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15047889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0400835101
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