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EBI2 Is a Negative Regulator of Type I Interferons in Plasmacytoid and Myeloid Dendritic Cells

Epstein-Barr virus induced receptor 2 (EBI2), a Gα(i)-coupled G protein-coupled receptor, is a chemotactic receptor for B, T and dendritic cells (DC). Genetic studies have also implicated EBI2 as a regulator of an interferon regulatory factor 7 (IRF7)-driven inflammatory network (IDIN) associated wi...

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Bibliographic Details
Main Authors: Chiang, Eugene Y., Johnston, Robert J., Grogan, Jane L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873289/
https://ncbi.nlm.nih.gov/pubmed/24386204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083457
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