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Biomolecular cryocrystallography: Structural changes during flash-cooling

To minimize radiation damage, crystal structures of biological macromolecules are usually determined after rapid cooling to cryogenic temperatures, some 150–200 K below the normal physiological range. The biological relevance of such structures relies on the assumption that flash-cooling is sufficie...

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Detalhes bibliográficos
Autor principal: Halle, Bertil
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387327/
https://ncbi.nlm.nih.gov/pubmed/15051877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308315101
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