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Biomolecular cryocrystallography: Structural changes during flash-cooling
To minimize radiation damage, crystal structures of biological macromolecules are usually determined after rapid cooling to cryogenic temperatures, some 150–200 K below the normal physiological range. The biological relevance of such structures relies on the assumption that flash-cooling is sufficie...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC387327/ https://ncbi.nlm.nih.gov/pubmed/15051877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308315101 |
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