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Frequency and origin of haplotypes associated with the beta-globin gene cluster in individuals with trait and sickle cell anemia in the Atlantic and Pacific coastal regions of Colombia

Sickle cell anemia is a genetic disease with high prevalence in people of African descent. There are five typical haplotypes associated with this disease and the haplotypes associated with the beta-globin gene cluster have been used to establish the origin of African-descendant people in America. In...

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Detalhes bibliográficos
Main Authors: Fong, Cristian, Lizarralde-Iragorri, María Alejandra, Rojas-Gallardo, Diana, Barreto, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado em: Sociedade Brasileira de Genética 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873178/
https://ncbi.nlm.nih.gov/pubmed/24385850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1415-47572013000400005
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