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Phase-1 trial of gefitinib and temozolomide in patients with malignant glioma: a North American brain tumor consortium study

PURPOSE: This is a phase-I study of gefitinib in combination with temozolomide in patients with gliomas. The goal of the study was to define the maximum tolerated dose (MTD) and to characterize the pharmacokinetics of gefitinib when combined with temozolomide. PATIENTS AND METHODS: Patients were str...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Prados, Michael D., Yung, W. K. A., Wen, Patrick Y., Junck, Larry, Cloughesy, Timothy, Fink, Karen, Chang, Susan, Robins, H. Ian, Dancey, Janet, Kuhn, John
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873156/
https://ncbi.nlm.nih.gov/pubmed/17694310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-007-0556-y
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