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Phase-1 trial of gefitinib and temozolomide in patients with malignant glioma: a North American brain tumor consortium study
PURPOSE: This is a phase-I study of gefitinib in combination with temozolomide in patients with gliomas. The goal of the study was to define the maximum tolerated dose (MTD) and to characterize the pharmacokinetics of gefitinib when combined with temozolomide. PATIENTS AND METHODS: Patients were str...
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| Asıl Yazarlar: | , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3873156/ https://ncbi.nlm.nih.gov/pubmed/17694310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-007-0556-y |
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