Hypoxia attenuates purinergic P2X receptor-induced inflammatory gene expression in brainstem microglia

Hypoxia and increased extracellular nucleotides are frequently coincident in the brainstem. Extracellular nucleotides are potent modulators of microglial inflammatory gene expression via P2X purinergic receptor activation. Although hypoxia is also known to modulate inflammatory gene expression, litt...

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Autores principales: Smith, Stephanie MC, Mitchell, Gordon S, Friedle, Scott A, Sibigtroth, Christine M, Vinit, Stéphane, Watters, Jyoti J
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873144/
https://ncbi.nlm.nih.gov/pubmed/24377098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/HP.S45529
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