Genome-wide association study identifies a potent locus associated with human opioid sensitivity

Opioids, such as morphine and fentanyl, are widely used as effective analgesics for the treatment of acute and chronic pain. In addition, the opioid system has a key role in the rewarding effects of morphine, ethanol, cocaine and various other drugs. Although opioid sensitivity is well known to vary...

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Detalhes bibliográficos
Main Authors: Nishizawa, D, Fukuda, K, Kasai, S, Hasegawa, J, Aoki, Y, Nishi, A, Saita, N, Koukita, Y, Nagashima, M, Katoh, R, Satoh, Y, Tagami, M, Higuchi, S, Ujike, H, Ozaki, N, Inada, T, Iwata, N, Sora, I, Iyo, M, Kondo, N, Won, M-J, Naruse, N, Uehara-Aoyama, K, Itokawa, M, Koga, M, Arinami, T, Kaneko, Y, Hayashida, M, Ikeda, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873034/
https://ncbi.nlm.nih.gov/pubmed/23183491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2012.164
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