Notch Signaling in Acute Promyelocytic Leukemia

Acute promyelocytic leukemia (APL) is initiated by the PML-RARA fusion oncogene and has a characteristic expression profile that includes high levels of the Notch ligand JAG1. In this study, we used a series of bioinformatic, in vitro, and in vivo assays to assess the role of Notch signaling in huma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Grieselhuber, Nicole R., Klco, Jeffery M., Verdoni, Angela M., Lamprecht, Tamara, Sarkaria, Shawn M., Wartman, Lukas D., Ley, Timothy J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872828/
https://ncbi.nlm.nih.gov/pubmed/23455394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.68
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