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Stretch-induced alternative splicing of serum response factor promotes bronchial myogenesis and is defective in lung hypoplasia

Smooth muscle (SM) develops only in organs and sites that sustain mechanical tensions. Therefore, we determined the role of stretch in mouse and human bronchial myogenesis. Sustained stretch induced expression of SM proteins in undifferentiated mesenchymal cells and accelerated the differentiation o...

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Detalhes bibliográficos
Main Authors: Yang, Yan, Beqaj, Safedin, Kemp, Paul, Ariel, Ilana, Schuger, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387248/
https://ncbi.nlm.nih.gov/pubmed/11104785
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