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Development of high drug-loading nanomicelles targeting steroids to the brain
The objective of this research was to develop and evaluate high drug-loading ligand-modified nanomicelles to deliver a steroidal compound to the brain. YC1 (5α-cholestane-24-methylene-3β, 5α, 6β, 19-tetraol), with poor solubility and limited access to the brain, for the first time, has been proved t...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove Medical Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3872275/ https://ncbi.nlm.nih.gov/pubmed/24379663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S52576 |
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