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Development of high drug-loading nanomicelles targeting steroids to the brain

The objective of this research was to develop and evaluate high drug-loading ligand-modified nanomicelles to deliver a steroidal compound to the brain. YC1 (5α-cholestane-24-methylene-3β, 5α, 6β, 19-tetraol), with poor solubility and limited access to the brain, for the first time, has been proved t...

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Detalhes bibliográficos
Main Authors: Zheng, Sijia, Xie, Yanqi, Li, Yuan, Li, Ling, Tian, Ning, Zhu, Wenbo, Yan, Guangmei, Wu, Chuanbin, Hu, Haiyan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872275/
https://ncbi.nlm.nih.gov/pubmed/24379663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S52576
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