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The Basis for Evolution of DNA-Binding Specificity of the Aft1 Transcription Factor in Yeasts

The Saccharomyces cerevisiae Aft1 and Kluyveromyces lactis KlAft are orthologous yeast transcription activators that regulate the expression of the same group of iron-uptake genes but bind to the different DNA sites: TGCACCC for Aft1 and PuCACCC for KlAft. To establish whether the DNA-binding mechan...

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Autores principales: Gonçalves, Isabelle R., Conde e Silva, Natalia, Garay, Cesar La Torre, Lesuisse, Emmanuel, Camadro, Jean Michel, Blaiseau, Pierre Louis
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872181/
https://ncbi.nlm.nih.gov/pubmed/24172132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.157693
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