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T-cell receptor alpha-chain gene is split in a human T-cell leukemia cell line with a t(11;14)(p15;q11).

Chromosomal rearrangements in malignant T-cell disease frequently involve the chromosome bands containing the T-cell receptor genes. The RPMI 8402 cell line, which was established from the leukemia cells of a patient with T-cell acute lymphoblastic leukemia, is characterized by a translocation invol...

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Detalhes bibliográficos
Main Authors: Le Beau, M M, McKeithan, T W, Shima, E A, Goldman-Leikin, R E, Chan, S J, Bell, G I, Rowley, J D, Diaz, M O
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387217/
https://ncbi.nlm.nih.gov/pubmed/3540949
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