Association of a Cystatin C Gene Variant With Cystatin C Levels, CKD, and Risk of Incident Cardiovascular Disease and Mortality

BACKGROUND: Carriers of the T allele of the single-nucleotide polymorphism rs13038305 tend to have lower cystatin C levels and higher cystatin C-based estimated glomerular filtration rate (eGFR(cys)). Adjusting for this genetic effect on cystatin C concentrations may improve GFR estimation, reclassi...

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Autors principals: O’Seaghdha, Conall M., Tin, Adrienne, Yang, Qiong, Katz, Ronit, Liu, YongMei, Harris, Tamara, Astor, Brad, Coresh, Josef, Fox, Caroline S., Kao, W.H. Linda, Shlipak, Michael G.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872167/
https://ncbi.nlm.nih.gov/pubmed/23932088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.ajkd.2013.06.015
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