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(+)-Grandifloracin, an antiausterity agent, induces autophagic PANC-1 pancreatic cancer cell death

Human pancreatic tumors are known to be highly resistant to nutrient starvation, and this prolongs their survival in the hypovascular (austere) tumor microenvironment. Agents that retard this tolerance to nutrient starvation represent a novel antiausterity strategy in anticancer drug discovery. (+)-...

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Detalhes bibliográficos
Main Authors: Ueda, Jun-ya, Athikomkulchai, Sirivan, Miyatake, Ryuta, Saiki, Ikuo, Esumi, Hiroyasu, Awale, Suresh
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872082/
https://ncbi.nlm.nih.gov/pubmed/24379655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S52168
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