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A monoclonal IgG anticardiolipin antibody from a patient with the antiphospholipid syndrome is thrombogenic in mice.

Antiphospholipid antibodies, including anticardiolipin antibodies (ACA), are strongly associated with recurrent thrombosis in patients with the antiphospholipid syndrome (APS). To date, reports about the binding specificities of ACA and their role(s) in causing and/or sustaining thrombosis in APS ar...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Olee, T, Pierangeli, S S, Handley, H H, Le, D T, Wei, X, Lai, C J, En, J, Novotny, W, Harris, E N, Woods, V L, Chen, P P
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38720/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8710918/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.16.8606
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