Acute tryptophan depletion alters the effective connectivity of emotional arousal circuitry during visceral stimuli in healthy women

OBJECTIVE: Alterations in serotonin signalling within the brain–gut axis have been implicated in the pathophysiology of irritable bowel syndrome (IBS) and is a treatment target. Acute tryptophan depletion (ATD) decreases brain serotonin (5-hydroxytryptamine; 5-HT) levels, and increases visceral perc...

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Main Authors: Labus, J S, Mayer, E A, Jarcho, J, Kilpatrick, L A, Kilkens, T O C, Evers, E A T, Backes, W H, Brummer, R-J M, van Nieuwenhoven, M A
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871999/
https://ncbi.nlm.nih.gov/pubmed/21402618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2010.213447
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