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Positive and negative roles of an initiator protein at an origin of replication.

The properties of mutants in the pir gene of plasmid R6K have suggested that the pi protein plays a dual role; it is required for replication to occur and also plays a role in the negative control of the plasmid copy number. In our present study, we have found that the pi level in cell extracts of E...

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Detalhes bibliográficos
Main Authors: Filutowicz, M, McEachern, M J, Helinski, D R
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387197/
https://ncbi.nlm.nih.gov/pubmed/3540947
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