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Strategies Targeting cAMP Signaling in the Treatment of Polycystic Kidney Disease
Polycystic kidney disease (PKD) is a leading cause of ESRD worldwide. In PKD, excessive cell proliferation and fluid secretion, pathogenic interactions of mutated epithelial cells with an abnormal extracellular matrix and alternatively activated interstitial macrophages, and the disruption of mechan...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Nephrology
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3871779/ https://ncbi.nlm.nih.gov/pubmed/24335972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013040398 |
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