Cysteamine Modulates Oxidative Stress and Blocks Myofibroblast Activity in CKD

Therapy to slow the relentless expansion of interstitial extracellular matrix that leads to renal functional decline in patients with CKD is currently lacking. Because chronic kidney injury increases tissue oxidative stress, we evaluated the antifibrotic efficacy of cysteamine bitartrate, an antioxi...

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Detalhes bibliográficos
Main Authors: Okamura, Daryl M., Bahrami, Nadia M., Ren, Shuyu, Pasichnyk, Katie, Williams, Juliana M., Gangoiti, Jon A., Lopez-Guisa, Jesus M., Yamaguchi, Ikuyo, Barshop, Bruce A., Duffield, Jeremy S., Eddy, Allison A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2014
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871767/
https://ncbi.nlm.nih.gov/pubmed/24009239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012090962
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