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On estimation of genetic variance within families using genome-wide identity-by-descent sharing

BACKGROUND: Traditionally, heritability and other genetic parameters are estimated from between-family variation. With the advent of dense genotyping, it is now possible to compute the proportion of the genome that is shared by pairs of sibs and thus undertake the estimation within families, thereby...

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Detalhes bibliográficos
Autor principal: Hill, William G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871764/
https://ncbi.nlm.nih.gov/pubmed/24007429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9686-45-32
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