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Role of Electrical Activity in Horizontal Axon Growth in the Developing Cortex: A Time-Lapse Study Using Optogenetic Stimulation

During development, layer 2/3 neurons in the neocortex extend their axons horizontally, within the same layers, and stop growing at appropriate locations to form branches and synaptic connections. Firing and synaptic activity are thought to be involved in this process, but how neuronal activity regu...

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Detalhes bibliográficos
Main Authors: Malyshevskaya, Olga, Shiraishi, Yoshihiro, Kimura, Fumitaka, Yamamoto, Nobuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871609/
https://ncbi.nlm.nih.gov/pubmed/24376616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082954
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