Cilengitide-Induced Temporal Variations in Transvascular Transfer Parameters of Tumor Vasculature in a Rat Glioma Model: Identifying Potential MRI Biomarkers of Acute Effects

Increased efficacy of radiotherapy (RT) 4-8 h after Cilengitide treatment has been reported. We hypothesized that the effects of Cilengitide on tumor transvascular transfer parameters might underlie, and thus predict, this potentiation. Athymic rats with orthotopic U251 glioma were studied at ~21 da...

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Detalhes bibliográficos
Main Authors: Nagaraja, Tavarekere N., Aryal, Madhava P., Brown, Stephen L., Bagher-Ebadian, Hassan, Mikkelsen, Tom, Yang, James J., Panda, Swayamprava, Keenan, Kelly A., Cabral, Glauber, Ewing, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871527/
https://ncbi.nlm.nih.gov/pubmed/24376814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084493
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