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Next-Generation Sequencing of Lung Cancer EGFR Exons 18-21 Allows Effective Molecular Diagnosis of Small Routine Samples (Cytology and Biopsy)

Selection of lung cancer patients for therapy with tyrosine kinase inhibitors directed at EGFR requires the identification of specific EGFR mutations. In most patients with advanced, inoperable lung carcinoma limited tumor samples often represent the only material available for both histologic typin...

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Autors principals: de Biase, Dario, Visani, Michela, Malapelle, Umberto, Simonato, Francesca, Cesari, Valentina, Bellevicine, Claudio, Pession, Annalisa, Troncone, Giancarlo, Fassina, Ambrogio, Tallini, Giovanni
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871524/
https://ncbi.nlm.nih.gov/pubmed/24376723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083607
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