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Polarized expression of a chimeric protein in which the transmembrane and cytoplasmic domains of the influenza virus hemagglutinin have been replaced by those of the vesicular stomatitis virus G protein.

In polarized epithelial cells, influenza virus buds exclusively from the apical domain of the plasma membrane, whereas vesicular stomatitis virus (VSV) buds exclusively from the basolateral domain. In virus-infected cells, the envelope proteins, influenza hemagglutinin (HA) and vesicular stomatitis...

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Main Authors: McQueen, N, Nayak, D P, Stephens, E B, Compans, R W
Formato: Artigo
Idioma:Inglês
Publicado: 1986
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC387129/
https://ncbi.nlm.nih.gov/pubmed/3025835
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