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Toward postnatal reversal of ocular congenital malformations

Aniridia is a panocular disorder that severely affects vision in early life. Most cases are caused by dominantly inherited mutations or deletions of the PAX6 gene, which encodes a transcription factor that is essential for the development of the eye and the central nervous system. In this issue of t...

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Hlavní autoři: Sahel, José-Alain, Marazova, Katia
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871257/
https://ncbi.nlm.nih.gov/pubmed/24355915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73560
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