Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection

Malaria, which is the result of Plasmodium falciparum infection, is a global health threat that resulted in 655,000 deaths and 216 million clinical cases in 2010 alone. Recent phase 3 trials with malaria vaccine candidate RTS,S/AS01 (RTS,S) in children has demonstrated modest efficacy against clinic...

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Main Authors: Foquet, Lander, Hermsen, Cornelus C., van Gemert, Geert-Jan, Van Braeckel, Eva, Weening, Karin E., Sauerwein, Robert, Meuleman, Philip, Leroux-Roels, Geert
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2013
Assuntos:
Brief Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871238/
https://ncbi.nlm.nih.gov/pubmed/24292709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70349
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