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Embryonic exposure to excess thyroid hormone causes thyrotrope cell death

Central congenital hypothyroidism (CCH) is more prevalent in children born to women with hyperthyroidism during pregnancy, suggesting a role for thyroid hormone (TH) in the development of central thyroid regulation. Using the zebrafish embryo as a model for thyroid axis development, we have characte...

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Autori principali: Tonyushkina, Ksenia N., Shen, Meng-Chieh, Ortiz-Toro, Theresa, Karlstrom, Rolf O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871235/
https://ncbi.nlm.nih.gov/pubmed/24316972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70038
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