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Sequential Cu(I)/Pd(0)-Catalyzed Multicomponent Coupling and Annulation Protocol for the Synthesis of Indenoisoquinolines

[Image: see text] Copper-catalyzed coupling of imines, vinylstannanes or alkynes and o-bromoaroyl chlorides followed by Pd(0)-catalyzed annulations afforded indenoisoquinolines. Protocols requiring minimal purifications were developed, providing new methods for the construction of combinatorial libr...

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Detalhes bibliográficos
Main Authors: Jayanth, Thiruvellore Thatai, Zhang, Lei, Johnson, Thomas S., Malinakova, Helena C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871195/
https://ncbi.nlm.nih.gov/pubmed/19159326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol802755z
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