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Chemoenzymatic synthesis and in situ application of S-adenosyl-L-methionine analogs
Analogs of S-adenosyl-L-methionine (SAM) are increasingly applied to the methyltransferase (MT) catalysed modification of biomolecules including proteins, nucleic acids, and small molecules. However, SAM and analogs suffer from an inherent instability, and their chemical synthesis is challenged by l...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3871182/ https://ncbi.nlm.nih.gov/pubmed/24100405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ob41702f |
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