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A synthetic peptide vaccine involving the product of the pre-S(2) region of hepatitis B virus DNA: protective efficacy in chimpanzees.

The S gene encoding the major surface polypeptide of hepatitis B virus is preceded by the region pre-S(2) with a capacity to code for 55 amino acid residues. In the product of region pre-S(2), the sequence of 19 amino acid residues (amino acids 14-32 from the N terminus) representing an area of high...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Itoh, Y, Takai, E, Ohnuma, H, Kitajima, K, Tsuda, F, Machida, A, Mishiro, S, Nakamura, T, Miyakawa, Y, Mayumi, M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387097/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3466181/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.23.9174
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