Polymorphism of HLA-DR beta chains in DR4, -7, and -9 haplotypes: implications for the mechanisms of allelic variation.

We have isolated and sequenced cDNA clones corresponding to the DR beta 1 and DR beta 2 loci from two homozygous B-cell lines typed as DR7 (Burkhart) and DR9 (ISK). These nucleotide sequences were compared to beta 1 and beta 2 chains of other DR haplotypes. The first-domain sequences of beta 2 chain...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gregersen, P K, Moriuchi, T, Karr, R W, Obata, F, Moriuchi, J, Maccari, J, Goldberg, D, Winchester, R J, Silver, J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387092/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3466180/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.23.9149
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