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Polymorphism of HLA-DR beta chains in DR4, -7, and -9 haplotypes: implications for the mechanisms of allelic variation.

We have isolated and sequenced cDNA clones corresponding to the DR beta 1 and DR beta 2 loci from two homozygous B-cell lines typed as DR7 (Burkhart) and DR9 (ISK). These nucleotide sequences were compared to beta 1 and beta 2 chains of other DR haplotypes. The first-domain sequences of beta 2 chain...

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Detalhes bibliográficos
Main Authors: Gregersen, P K, Moriuchi, T, Karr, R W, Obata, F, Moriuchi, J, Maccari, J, Goldberg, D, Winchester, R J, Silver, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387092/
https://ncbi.nlm.nih.gov/pubmed/3466180
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